ARN21929
ARN21929 is a topoisomerase II (TopoisomeraseII) inhibitor with an IC50 of 4.5 μM. It exhibits favorable kinetic and thermodynamic solubility and metabolic stability. However, ARN21929 shows poor antiproliferative activity against A549, DU145, MCF7, HeLa, and A375 cells. It is useful for tumor research.
Product Specifications
CAS Number
2230854-98-3
Field of Research
Molecular Biology
Smiles
FC=1C=CC=CC1NC2=NC (=NC3=C2CNCC3) C=4C=CN=CC4
Molecular Formula
C18H16FN5
Molecular Weight
321.35
Storage Conditions
-20°C
Notes
For research use only.
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