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Nampt-IN-16

Nampt-IN-16 (Compound 9a) is an orally active NAMPT inhibitor with an IC50 of 0.15 μM. It reduces intracellular NAD+ and ATP levels. Nampt-IN-16 inhibits the proliferation, migration, and invasion of gastric cancer cells, induces cell cycle arrest and apoptosis, and alters cellular metabolism. This compound is applicable for research in tumors such as gastric cancer.

Product Specifications

CAS Number

3077970-44-3

Field of Research

Cell Biology, Metabolism Research

Smiles

O=C (OCC=1C=NC=CC1) NC2=CC=C (C=C2) CNC (=O) C3=CC (F) =CC=C3N4CCCC4

Molecular Formula

C25H25FN4O3

Molecular Weight

448.49

Storage Conditions

-20°C

Notes

For research use only.

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