LY3526318
LY3526318 is an orally active, selective TRPA1 antagonist with an IC50 of 5-6 μM. It blocks the TRPA1 channel, inhibiting pain signal transduction mediated by this channel and demonstrating analgesic activity. LY3526318 is primarily utilized in research related to chronic pain, such as diabetic peripheral neuropathic pain, chronic lower back pain, and osteoarthritis-induced pain.
Product Specifications
CAS Number
1889218-34-1
Field of Research
Pharmacology & Drug Discovery
Smiles
[C@@H] (C (NC=1N=C (C=CC1) C=2C=NC (C (F) (F) F) =NC2) =O) (C) N3C4=C (N (C) C (=O) N (CC5=NC (C) =NO5) C4=O) N=C3
Molecular Formula
C23H19F3N10O4
Molecular Weight
556.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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