Simepdekinra
Simepdekinra (Compound 221) is a potent IL-17A modulator with IC50 values ≤10 nM for IL-17A/A HEK-Blue cells and 10–100 nM for IL-17A/F HEK-Blue cells, suitable for studying psoriasis, ankylosing spondylitis, and psoriatic arthritis.
Product Specifications
CAS Number
2978700-29-5
Field of Research
Immunology & Inflammation
Purity
99.96% (May vary between batches)
Smiles
[C@H] ([C@H] (NC (=O) C=1N (CC) N=CC1) C (NC2=C (F) C=C ([C@@H] ([C@H] (C (=O) N3C[C@@H] (C) N (C) CC3) NC ([C@@H] (OC) C) =O) C) C=C2) =O) (C4CC4) C5CC5
Molecular Formula
C35H50FN7O5
Molecular Weight
667.81
Storage Conditions
-20°C
Notes
For research use only.
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