MOMA-341
MOMA-341 is a selective, ATP-competitive WRN allosteric inhibitor that binds to the cysteine 727 site of WRN. It induces DNA damage, cell death, and tumor regression in dMMR/MSI-H mouse models and can be used to study advanced and metastatic solid tumors.
Product Specifications
CAS Number
3078276-74-8
Field of Research
Cell Biology, Molecular Biology
Smiles
C (=O) (N1[C@@]2 (C3=C (N (N=C3CCN (C (C=C) =O) C2) C4=C (O) C=C (C=C4) C5CC5) CC1) [H]) C=6C (N) =C (F) C (C (F) (F) F) =NC6
Molecular Formula
C28H26F4N6O3
Molecular Weight
570.54
Storage Conditions
-20°C
Notes
For research use only.
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