BRD4-BD1/2-IN-3
BRD4-BD1/2-IN-3 is a highly selective BRD4 BD2 inhibitor (IC50 = 0.41 nM) that exhibits strong selectivity over BRD4 BD1 and potently suppresses LPS-induced IL-6 expression. BRD4-BD1/2-IN-3 modulates TNF and NF-κB signaling pathways, providing a valuable tool for studying BRD4 biology and for researches on inflammatory diseases.
Product Specifications
CAS Number
3106588-54-6
Field of Research
Epigenetics & Chromatin, Immunology & Inflammation; Epigenetics & Chromatin
Purity
99.63% (May vary between batches)
Smiles
O=C1N=C (NC=2C=C (OC) C=C (OC) C12) C=3C=NN (C3) CC=4C=CC=CC4
Molecular Formula
C20H18N4O3
Molecular Weight
362.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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