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BRD4-BD1/2-IN-3

BRD4-BD1/2-IN-3 is a highly selective BRD4 BD2 inhibitor (IC50 = 0.41 nM) that exhibits strong selectivity over BRD4 BD1 and potently suppresses LPS-induced IL-6 expression. BRD4-BD1/2-IN-3 modulates TNF and NF-κB signaling pathways, providing a valuable tool for studying BRD4 biology and for researches on inflammatory diseases.

Product Specifications

CAS Number

3106588-54-6

Field of Research

Epigenetics & Chromatin, Immunology & Inflammation; Epigenetics & Chromatin

Purity

99.63% (May vary between batches)

Smiles

O=C1N=C (NC=2C=C (OC) C=C (OC) C12) C=3C=NN (C3) CC=4C=CC=CC4

Molecular Formula

C20H18N4O3

Molecular Weight

362.39

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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