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C105SR

C105SR is a cyclophilin D (CypD) inhibitor targeting peptidyl-prolyl cis-trans isomerase (PPIase) . It has an IC50 value of 5 nM for inhibiting mitochondrial permeability transition pore (mPTP) opening. C105SR reduces apoptosis in hepatocytes induced by hypoxia-reoxygenation and boosts calcium retention capacity (CRC) . It demonstrates hepatoprotective effects in a mouse model of ischemia-reperfusion injury (IRI) .

Product Specifications

Field of Research

Cell Biology, Protein Biochemistry

Molecular Formula

C32H33BrN4O3S

Molecular Weight

633.60

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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