C105SR
C105SR is a cyclophilin D (CypD) inhibitor targeting peptidyl-prolyl cis-trans isomerase (PPIase) . It has an IC50 value of 5 nM for inhibiting mitochondrial permeability transition pore (mPTP) opening. C105SR reduces apoptosis in hepatocytes induced by hypoxia-reoxygenation and boosts calcium retention capacity (CRC) . It demonstrates hepatoprotective effects in a mouse model of ischemia-reperfusion injury (IRI) .
Product Specifications
Field of Research
Cell Biology, Protein Biochemistry
Molecular Formula
C32H33BrN4O3S
Molecular Weight
633.60
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog