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PROTAC SARS-CoV-2 Mpro degrader-3

PROTACSARS-CoV-2 Mpro degrader-3 (Compound P2) exhibits antiviral activity by degrading the main protease (Mpro) of human coronaviruses (HCoV) with a DC50 of 27 μM. It effectively inhibits viral replication, with EC50 values of 4.6 μM for HCoV-229E and HCoV-OC43, and 0.71 μM for SARS-CoV-2.

Product Specifications

Field of Research

Infectious Disease & Virology, Pharmacology & Drug Discovery

Molecular Formula

C53H73N10NaO14S2

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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