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LTA4H-IN-5

LTA4H-IN-5 (Compound H122) is an orally active inhibitor of leukotriene A4 hydrolase (LTA4H), effectively suppressing both its aminopeptidase and hydrolase activities with IC50 values of 0.38 nM and 16.93 nM, respectively. In C57 mice, it demonstrates favorable pharmacokinetic properties and shows efficacy in improving DNBS-induced ulcerative colitis in rat models.

Product Specifications

Field of Research

Metabolism Research

Molecular Formula

C18H17Cl2FN4O4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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