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SGC8158

SGC8158 is an inhibitor of PRMT7 and is useful for studying the cellular function of PRMT7. It reduces the monomethyl arginine levels of Hsp70 (a common substrate of PRMT7) . SGC8158 can inhibit the growth of various cancer cells (IC50: 2-9 μM) and multidrug-resistant (MDR) cancer cells, and it also enhances the DNA damage and cytotoxicity induced by Doxorubicin.

Product Specifications

Field of Research

Epigenetics & Chromatin

Molecular Formula

C27H31ClN6O3S

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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