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Paclitaxel-2′-succinate NHS ester

Paclitaxel-2′-succinate NHS ester is a derivative of paclitaxel featuring a succinate linker with its carboxyl group activated as an NHS ester. The NHS ester moiety exhibits high reactivity towards amino or hydroxyl groups, facilitating its conjugation with various molecules (such as peptides, proteins, antibodies, enzymes, or polymers) . This compound is utilized in the development of nanomedicines and cancer research.

Product Specifications

CAS Number

245110-80-9

Field of Research

Pharmacology & Drug Discovery, Signal Transduction

Smiles

O (C (C) =O) [C@]12[C@]3 ([C@H] (OC (=O) C4=CC=CC=C4) [C@@]5 (O) C (C) (C) C ([C@@H] (OC (C) =O) C (=O) [C@]3 (C) [C@@H] (O) C[C@]1 (OC2) [H]) =C (C) [C@@H] (OC ([C@@H] ([C@@H] (NC (=O) C6=CC=CC=C6) C7=CC=CC=C7) OC (CCC (ON8C (=O) CCC8=O) =O) =O) =O) C5) [H]

Molecular Formula

C55H58N2O19

Molecular Weight

1051.05

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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