PF-06442609
PF-06442609 is an orally active γ-secretase modulator with an IC50 value of 6 nM for Aβ42. It exhibits good CNS permeability.
Product Specifications
CAS Number
1402002-76-9
Field of Research
Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology
Smiles
O=C1N2C (C (=O) N ([C@H] (COC3=C ([C@H] (C (F) (F) F) C) C=C (F) C=C3) C) CC2) =CC=C1N4C=NC (C) =C4
Molecular Formula
C24H24F4N4O3
Molecular Weight
492.47
Storage Conditions
-20°C
Notes
For research use only.
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