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CDK4/6-IN-15 hydrochloride

CDK4/6-IN-15 hydrochloride is an orally active selective inhibitor of CDK4/6. It effectively restrains the growth of cancer cells by arresting the cell cycle at the G1 phase. Additionally, CDK4/6-IN-15 hydrochloride inhibits phosphorylation of the retinoblastoma tumor suppressor protein (Rb) at site S780 and suppresses E2 factor (E2F) -regulated gene expression.

Product Specifications

Field of Research

Cell Biology, Signal Transduction

Molecular Formula

C21H28ClFN8S

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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