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PROTAC ALK degrader-2

PROTACALK degrader-2 (B1-PEG) is a PROTAC-based ALK degrader with a DC50 of 45 nM in H3122 EML4-ALK DC50 (GSH+) . Through PEGylation, PROTACALK degrader-2 can self-assemble into micelles in water, releasing its active form in tumor-specific high-GSH environments.

Product Specifications

Field of Research

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Molecular Formula

C55H70ClN11O12S3. (C2H4O) n

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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