7-tert-Butylfascaplysin
7-tert-Butylfascaplysin (7-TB) is a derivative of Fascaplysin, isolated from Fascaplysinopsis sp. It induces replication stress, leading to toxic DNA double-strand breaks and apoptosis-like cell death, exhibiting nanomolar cytotoxicity against cancer cells. Additionally, 7-tert-Butylfascaplysin demonstrates DNA intercalation activity, with an EC50 of 3.2 μM.
Product Specifications
Field of Research
Cell Biology, Signal Transduction
Molecular Formula
C22H19ClN2O
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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