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Leuxinostat

Leuxinostat, an inhibitor of HDAC, exhibits an IC50 of 30 nM against hHDAC6. It suppresses the proliferation of THP1, K562, U937, and MEK1 cells, while also inducing apoptosis in leukemia cells NB4 and MOLT-4. Additionally, Leuxinostat inhibits the expansion of hematopoietic stem cells and demonstrates anti-leukemic activity in a zebrafish model.

Product Specifications

Field of Research

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Molecular Formula

C18H20N4O4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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