PROTAC ALK degrader-1
PROTACALK degrader-1 (compound B1) is a PROTACs-based ALK degrader with a DC50 of 26 nM in H3122 EML4-ALK. It is utilized in creating PROTACALK degrader-2, which boasts excellent bioavailability.
Product Specifications
CAS Number
3049802-45-8
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Smiles
O=C1NC (=O) C (N2C (=O) C=3C=CC=C (NCCNC (=O) CNC (=O) CN4CCC (C5=CC (OC (C) C) =C (C=C5C) NC6=NC=C (Cl) C (=N6) NC=7C=CC=CC7S (=O) (=O) C (C) C) CC4) C3C2=O) CC1
Molecular Formula
C47H55ClN10O9S
Molecular Weight
971.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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