CB-0821
CB-0821 is a high-affinity CCR5 inhibitor with a Ki of 0.04 nM. It effectively binds to the hydrophobic pocket of the CCR5 protein, hindering the interaction between viral proteins and CCR5, thereby blocking virus entry. CB-0821 holds potential for anti-HIV research.
Product Specifications
CAS Number
81430-62-8
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry
Smiles
N1=C2N=C (C=C (C=3C=CC=CC3) N2N=C1CC=4N=C5N=C (C=C (C=6C=CC=CC6) N5N4) C=7C=CC=CC7) C=8C=CC=CC8
Molecular Formula
C35H24N8
Molecular Weight
556.62
Storage Conditions
-20°C
Notes
For research use only.
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