MS181
MS181 (compound 1) is an efficient PROTAC degrader that recruits cereblon (CRBN) and binds to the ubiquitin complex polycomb repressive complex 1 (PRC1) . It reduces the expression of EED, EZH2, SUZ12, BMI1, and RING1B, and exhibits antiproliferative activity.
Product Specifications
Field of Research
Pharmacology & Drug Discovery, Protein Biochemistry
Molecular Formula
C39H41N11O6
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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