Thailanstatin A cyclohexane diamine formic

Thailanstatin A cyclohexane diamine formic is an analogue of Spliceostatin. It effectively inhibits the proliferation of various cells, including N87 (IC50 = 0.33 μM), BT474 (IC50 = 0.34 μM), MDA-MB-361-DYT2 (IC50 = 0.88 μM), and MDA-MB-468 (IC50 = 0.27 μM) . Additionally, Thailanstatin A cyclohexane diamine formic can be utilized as a drug-linker conjugate in ADC (antibody-drug conjugate) molecules.