Influenza A virus-IN-14
Influenza A virus-IN-14 (Compound 37) is an inhibitor of the influenza A virus (IAV), effectively suppressing H1N1 with an EC50 of 23 nM. It demonstrates low cytotoxicity, with a CC50 exceeding 100 μM, and reduces cytopathic effects while enhancing the survival rate of Calu3 cells. The compound exhibits synergistic effects with the neuraminidase inhibitor Oseltamivir. However, it shows poor pharmacokinetic properties in CD-1 mice.
Product Specifications
Field of Research
Infectious Disease & Virology
Molecular Formula
C22H25F3N2O4
Storage Conditions
-20°C
Notes
For research use only.
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