BRD4 degrader-2
BRD4 degrader-2 (Compound JP-2-197) is a covalent and monovalent molecule glue-type BRD4 degrader. It targets RNF126 (E3 ligase) to degrade both long and short isoforms of BRD4 in cells.
Product Specifications
CAS Number
3036530-43-2
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery, Protein Biochemistry
Smiles
CC=1C2=C (N3C ([C@H] (CC (=O) N4CCN (C (/C=C/C (=O) C5=CC=C (OC) C=C5) =O) CC4) N=C2C6=CC=C (Cl) C=C6) =NN=C3C) SC1C
Molecular Formula
C34H33ClN6O4S
Molecular Weight
657.18
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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