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LLC355

LLC355 is a discoidin domain receptor 1 (DDR1) ATTEC degrader. It efficiently degrades DDR1 protein, with a DC50 value of 150.8 nM in non-small cell lung cancer NCI-H23 cells. LLC355 induces DDR1 degradation via lysosome-mediated autophagy and effectively inhibits the tumorigenicity, migration, and invasion of cancer cells.

Product Specifications

Field of Research

Pharmacology & Drug Discovery, Signal Transduction

Molecular Formula

C63H64ClF3N10O5

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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