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MPD2

MPD2 is a PROTAC compound based on a Cereblon-binding ligand that degrades the main protease MPro of SARS-CoV-2. In 293T cells, it effectively reduces MPro protein levels with a DC50 of 296 nM and shows time-dependent activity. MPD2 exhibits strong antiviral properties against various SARS-CoV-2 strains and has increased potency against Nirmatrelvir-resistant variants. It holds potential for researching SARS-CoV-2 diseases.

Product Specifications

Field of Research

Infectious Disease & Virology, Neuroscience, Pharmacology & Drug Discovery

Molecular Formula

C51H68N6O13

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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