SIRT-IN-4

SIRT-IN-4 is an inhibitor specifically targeting the NAD+-dependent lysine deacetylase Sirtuin2 (Sirt2) with an IC50 of 0.35 μM. It effectively inhibits Sirt2 deacetylation, thereby reducing cell viability and impeding the migration of prostate cancer cells. SIRT-IN-4 is useful for research on Sirt2's roles in cell cycle regulation and gene expression control.