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Proquazone

Proquazone (RU 43-715) is a chemically distinctive non-steroidal anti-inflammatory agent (NSAID) and an inhibitor of calcium sensing receptor (CaSR) . unlike most other NSAIDs, Proquazone does not have a free acid group in its structure. Proquazone may inhibit or arrest progression of bone erosions. Proquazone is an orally active anti-inflammatory, analgesic and anti-pyretic agent[1].

Product Specifications

Product Name Alternative

RU 43-715; Sandoz-43-715

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

CaSR

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/proquazone.html

Solubility

10 mM in DMSO

Smiles

O=C1N(C(C)C)C2=C(C=CC(C)=C2)C(C3=CC=CC=C3)=N1

Molecular Formula

C18H18N2O

Molecular Weight

278.35

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-17491/Proquazone-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-17491/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

CAS Number

[22760-18-5]

Available Sizes

Curated Selection

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