Pan-KRAS-IN-13
Pan-KRAS-IN-13 (compound 2) is a potent inhibitor of KRAS, exhibiting IC50 values of 2.75 nM and 2.89 nM for its G12D and G12V mutations, respectively.
Product Specifications
CAS Number
3033637-76-9
Field of Research
Signal Transduction
Smiles
FC1=C2C=3C (N4[C@@] (CCOC3N=C1C=5C6=C (C=C (O) C5) C=CC (F) =C6C#C) (CNCC4) [H]) =NC (OC[C@@]78N (C[C@H] (F) C7) CCC8) =N2
Molecular Formula
C33H31F3N6O3
Molecular Weight
616.63
Storage Conditions
-20°C
Notes
For research use only.
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