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FGFR4-IN-19

FGFR4-IN-19 (compound 8B) is a potent covalent inhibitor of fibroblast growth factor receptor 4 (FGFR4) with an IC50 value of 1.2 nM. It achieves high efficiency and selectivity by covalently targeting the rare cysteine (C552) in the FGFR4 kinase domain. FGFR4-IN-19 is applicable for hepatocellular carcinoma (HCC) research.

Product Specifications

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Molecular Formula

C21H14Cl3N5O4

Storage Conditions

-20°C

Notes

For research use only.

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