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IOX5

IOX5 is a selective prolyl hydroxylase (PHD) inhibitor with an IC50 of 0.19 μM for PHD2. In acute myeloid leukemia (AML) cells, IOX5 can stabilize HIF-1α, inhibit cell proliferation, and induce apoptosis. It exhibits anti-leukemia activity.

Product Specifications

Field of Research

Cell Biology, Epigenetics & Chromatin, Metabolism Research

Molecular Formula

C17H19F3N4O2

Storage Conditions

-20°C

Notes

For research use only.

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