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Gal-ARV-771

Gal-ARV-771 is a PROTAC prodrug, modified with galactose, based on ARV-771. It is activated in senescent cancer cells that express SA-β-Gal, thereby releasing ARV-771. Through the ubiquitin-proteasome pathway, Gal-ARV-771 induces selective degradation of the BRD4 protein in senescent cells and promotes apoptosis (apoptosis) of these cancer cells.

Product Specifications

Field of Research

Cell Biology, Epigenetics & Chromatin, Neuroscience, Pharmacology & Drug Discovery

Molecular Formula

C71H84ClN9O19S2

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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