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PTPN2/1-IN-3

PTPN2/1-IN-3 (compound 4) is an orally active PTPN2/N1 inhibitor, developed as an improved version of ABBV-CLS-484. It demonstrates antitumor activity, with an IC50 of 9.3 nM for inhibiting PTPN2, and exhibits oral bioavailability of 93% in mice.

Product Specifications

Field of Research

Cell Biology, Metabolism Research

Molecular Formula

C14H18FN3O4S

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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