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Antileishmanial agent-27

Antileishmanial agent-27 (compound 7j) is a benzothiazole-coumarin derivative. It acts as a competitive inhibitor of arginyl-tRNA synthetase (ArgRS) . This compound demonstrates selectivity towards the Leishmania donovani ArgRS (LdArgRS) over the human counterpart (HsArgRS), with IC50 values of 1.2 μM and 19 μM, respectively. Additionally, Antileishmanial agent-27 exhibits favorable pharmacokinetic properties.

Product Specifications

Field of Research

Infectious Disease & Virology

Molecular Formula

C24H16BrNO3S2

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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