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PROTAC BTK Degrader-9

PROTACBTK Degrader-9 (compound 23) is a potent PROTACs degrader that specifically targets BTK. It effectively downregulates the RANKL-activated BTK-PLCγ2-Ca2+-NFATc1 signaling pathway. Consequently, PROTACBTK Degrader-9 inhibits osteoclastogenesis and reduces alveolar bone resorption in a mouse model of periodontitis.

Product Specifications

Field of Research

Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Molecular Formula

C46H52FN13O5

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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