PNK1 (phospho-Ser114/Thr118) rabbit pAb
This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay. [provided by RefSeq, Sep 2010],
Product Specifications
Background
This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.[provided by RefSeq, Sep 2010]
UniProt
Q96T60
Swiss Prot
Q96T60
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized phosho peptide around human PNK1 (Ser114 and Thr118)
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Molecular Weight
57kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
57kD
Fragment
IgG
Subcellular Location
Nucleus . Chromosome . Localizes to site of double-strand breaks. .
Other Product Names
Bifunctional polynucleotide phosphatase/kinase (DNA 5'-kinase/3'-phosphatase) (Polynucleotide kinase-3'-phosphatase) [Includes: Polynucleotide 3'-phosphatase (EC 3.1.3.32) (2' (3') -polynucleotidase) ; Polynucleotide 5'-hydroxyl-kinase (EC 2.7.1.78) ]
Gene ID (Human)
11284
Available Sizes
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