H-Pro-Gly-Pro-OH

H-Pro-Gly-Pro-OH is a collagen-derived matrikine that has classically been described as a neutrophil chemoattractant. H-Pro-Gly-Pro-OH is perfectly positioned to focus neutrophils on the site required and direct a localized repair response. H-Pro-Gly-Pro-OH activates the transcription of neurotrophins and their receptor genes after cerebral ischemia[1][2].

Product Specifications

CAS Number

[7561-51-5]

Product Name Alternative

Pro-Gly-Pro

UNSPSC

12352209

Target

Drug Derivative

Type

Peptides

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/h-pro-gly-pro-oh.html

Purity

99.79

Solubility

H2O : 125 mg/mL (ultrasonic)

Smiles

O=C([C@@H]1CCCN1)NCC(N2[C@@H](CCC2)C(O)=O)=O

Molecular Formula

C12H19N3O4

Molecular Weight

269.30

References & Citations

[1]Patel DF, et al. The multifaceted roles of the matrikine Pro-Gly-Pro in pulmonary health and disease. Eur Respir Rev. 2018 Jun 27;27 (148) :180017.|[2]Dmitrieva VG, et al. Semax and Pro-Gly-Pro activate the transcription of neurotrophins and their receptor genes after cerebral ischemia. Cell Mol Neurobiol. 2010 Jan;30 (1) :71-9.