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LM-021

LM-021, a coumarin-chalcone derivative, exhibits properties such as anti-aggregation, antioxidant, neuroprotective, and anti-inflammatory effects. It inhibits the production of nitric oxide (NO), IL-1β, IL-6, and TNF-α, as well as the expression of CD68 and MHCII. Additionally, LM-021 reduces caspase 1 activity, lactate dehydrogenase release, and ROS level elevation. It is used in neurological research.

Product Specifications

CAS Number

1022282-98-9

Field of Research

Cell Biology, Immunology & Inflammation, Metabolism Research, Protein Biochemistry, Signal Transduction

Smiles

OC=1C=2C (OC (=O) C1C (/C=C/C3=CC=C (N (C) C) C=C3) =O) =CC=CC2

Molecular Formula

C20H17NO4

Molecular Weight

335.35

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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