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GluN2B-NMDAR antagonist-2

GluN2B-NMDAR antagonist-2 (compound S-58) is an effective and selective NMDAR-GluN2B antagonist that can cross the blood-brain barrier, with an IC50 value of 74.01 nM. It exhibits mild cytotoxicity and reduces both infarct size and neurological deficit scores in the brain, indicating its potential for stroke research.

Product Specifications

Field of Research

Neuroscience, Neuroscience; Pharmacology & Drug Discovery, Pharmacology & Drug Discovery

Molecular Formula

C24H25Cl2N3O3

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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