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Keap1-Nrf2-IN-18

Keap1-Nrf2-IN-18 (Compound 22) is an orally active inhibitor of the Keap1-Nrf2 protein-protein interaction (PPI), demonstrating favorable pharmacokinetic (PK) properties and enhanced in vivo efficacy in rats. In structure-activity relationship (SAR) studies, Keap1-Nrf2-IN-18 exhibits the strongest inhibitory activity (KD = 0.0029 μM) .

Product Specifications

Field of Research

Cancer Biology, Immunology & Inflammation

Molecular Formula

C27H29FN2O4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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