Imidazenil
Product Specifications
UNSPSC Description
Imidazenil is a partial positive allosteric modulator of GABAA receptors with anxiolytic, antipanic and anticonvulsant activities.
Target Antigen
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/imidazenil.html
Purity
98.95
Solubility
DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C(C1=C2CN=C(C3=C(Br)C=CC=C3)C4=C(C=CC(F)=C4)N2C=N1)N
Molecular Weight
399.22
References & Citations
[1]Giusti P, Ducić I, Puia G, et al. Imidazenil: a new partial positive allosteric modulator of gamma-aminobutyric acid (GABA) action at GABAA receptors. J Pharmacol Exp Ther. 1993;266(2):1018-1028.|[2]Thompson DM, Auta J, Guidotti A, Costa E. Imidazenil, a new anxiolytic and anticonvulsant drug, attenuates a benzodiazepine-induced cognition deficit in monkeys. J Pharmacol Exp Ther. 1995;273(3):1307-1312.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-121393/Imidazenil-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-121393/Imidazenil-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
151271-08-8
Available Sizes
Curated Selection
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