PZ-1922 free base
PZ-1922 free base is a brain-penetrant 5-HT6R/5-HT3R antagonist with Ki values of 17 nM and 0.45 nM, respectively. It reversibly inhibits MAO-B (pIC50: 8.93) . In rat novel object recognition (NOR) tests, PZ-1922 free base counteracts Scopolamine (SCOP) -induced memory deficits and prevents Aβ-induced memory decline in T-maze tests.
Product Specifications
CAS Number
1648745-65-6
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
ClC1=CC=CC (=C1) CN2C=CC=3C (=NC=4C=CC=CC4C32) N5CCNCC5
Molecular Formula
C22H21ClN4
Molecular Weight
376.88
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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