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PZ-1922 free base

PZ-1922 free base is a brain-penetrant 5-HT6R/5-HT3R antagonist with Ki values of 17 nM and 0.45 nM, respectively. It reversibly inhibits MAO-B (pIC50: 8.93) . In rat novel object recognition (NOR) tests, PZ-1922 free base counteracts Scopolamine (SCOP) -induced memory deficits and prevents Aβ-induced memory decline in T-maze tests.

Product Specifications

CAS Number

1648745-65-6

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Smiles

ClC1=CC=CC (=C1) CN2C=CC=3C (=NC=4C=CC=CC4C32) N5CCNCC5

Molecular Formula

C22H21ClN4

Molecular Weight

376.88

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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