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FLT3/CHK1-IN-2

FLT3/CHK1-IN-2 (Compound 30) is a dual inhibitor targeting FLT3 and CHK1, with IC50 values of 25.63 nM for CHK1, 16.39 nM for FLT3-WT, and 22.80 nM for FLT-D835Y. It displays favorable oral pharmacokinetic properties and kinase selectivity. FLT3/CHK1-IN-2 is applicable in acute myeloid leukemia (AML) research.

Product Specifications

Field of Research

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin; Cell Biology, Signal Transduction

Molecular Formula

C18H23F3N6O2S

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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