JAK1/2-IN-1
JAK1/2-IN-1 is a potent inhibitor of JAK1 and JAK2, with IC50 values of 0.4 nM and 8.1 nM, respectively. Additionally, JAK1/2-IN-1 inhibits IL-4 and IL-13, with IC50 values of 136.5 nM and 19.1 nM, respectively (WO2023244775A1; Example 33a) .
Product Specifications
CAS Number
3023876-01-6
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Immunology & Inflammation, Signal Transduction, Stem Cell & Developmental Biology
Smiles
C (F) (F) (F) C1=C2C (=CC (NC=3N=C (N[C@@H]4[C@@H] (C#N) CCOC4) C (C) =CN3) =C1) COB2O
Molecular Formula
C19H19BF3N5O3
Molecular Weight
433.19
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
