Antibacterial agent 182

Antibacterialagent 182 (compound 8c) is an antibacterial agent that exhibits activity against various Gram-positive bacteria, particularly displaying efficacy against vancomycin-resistant Enterococcus faecium (MIC ≤0.125 μg/mL) . At sub-MIC levels, Antibacterialagent 182 can inhibit biofilm formation by Staphylococcus aureus and Pseudomonas aeruginosa.