SARS-CoV-2-IN-81
SARS-CoV-2-IN-81 (compound 12e) is an effective AAK1 inhibitor with an IC50 value of 9.38 nM. It demonstrates antiviral activity against SARS-CoV-2 by reducing AAK1-induced phosphorylation of threonine 156 on AP2M1 and disrupting the direct interaction between AP2M1 and ACE2, ultimately inhibiting SARS-CoV-2 infection.
Product Specifications
Field of Research
Infectious Disease & Virology, Neuroscience
Molecular Formula
C25H20N4O2
Storage Conditions
-20°C
Notes
For research use only.
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