CBI1
CBI1 is a covalent BAX inhibitor. It selectively derivatizes BAX at C126 and inhibits BAX activation by triggering a ligand or through point mutations. CBI1 prevents the lipidation and oligomerization of BAX by t-2-hex. It also inhibits BAX activation induced by BH3 ligands, F116A mutation, or t-2-hex.
Product Specifications
Field of Research
Cell Biology
Smiles
BrC1=CC=C (C2=NNC (C (NCCCSSCCN) =O) =C2) C=C1
Molecular Formula
C15H19BrN4OS2
Molecular Weight
415.37
Storage Conditions
-20°C
Notes
For research use only.
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