WD6305
WD6305 is an effective and selective METTL3-METTL14 PROTAC degrader, with DC50 values of 140 nM and 194 nM for METTL3 and METTL14, respectively. It inhibits m6A modification and the proliferation of acute myeloid leukemia cells while inducing apoptosis. WD6305 also exhibits antitumor activity.
Product Specifications
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Molecular Formula
C61H75F2N11O5S
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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