PROTAC SARS-CoV-2 Mpro degrader-2
PROTACSARS-CoV-2 Mpro degrader-2 (Compound 6) is a potent SARS-CoV-2 Mpro PROTAC degrader. It exhibits broad-spectrum antiviral activity against coronaviruses, including SARS-CoV-2 (EC50 = 10.8 μM), HCoV-OC43 (EC50 = 1.6 μM), and HCoV-229E (EC50 = 6.5 μM) . In Calu-3 cells, it shows effective anti-SARS-CoV-2 activity with an EC50 of 0.89 μM.
Product Specifications
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery
Molecular Formula
C48H56ClN7O7S
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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