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PROTAC SARS-CoV-2 Mpro degrader-2

PROTACSARS-CoV-2 Mpro degrader-2 (Compound 6) is a potent SARS-CoV-2 Mpro PROTAC degrader. It exhibits broad-spectrum antiviral activity against coronaviruses, including SARS-CoV-2 (EC50 = 10.8 μM), HCoV-OC43 (EC50 = 1.6 μM), and HCoV-229E (EC50 = 6.5 μM) . In Calu-3 cells, it shows effective anti-SARS-CoV-2 activity with an EC50 of 0.89 μM.

Product Specifications

Field of Research

Infectious Disease & Virology, Pharmacology & Drug Discovery

Molecular Formula

C48H56ClN7O7S

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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