RIPK1-IN-20
RIPK1-IN-20 has strong RIPK1 kinase inhibitory activity with an IC50 value of 59.8 nM. It can block TNFα-induced necroptosis in both human and mouse cells, with an EC50 ranging from 1.06 to 4.58 nM.
Product Specifications
CAS Number
3026543-19-8
Field of Research
Cell Biology, Signal Transduction
Smiles
O=C1NN=C (N) C=2C (=CN (C12) CC3 (C) COC3) C=4C=CC5=C (C4) CCN5C (=O) CC=6C=CC=C (OC (F) (F) F) C6
Molecular Formula
C28H26F3N5O4
Molecular Weight
553.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
NBP3-07780-100ug 100 µg
Mouse Monoclonal ACE/CD143 Antibody (ACE/3765)
Sign In for Pricing
View Details MBS7182873 Inquire
Rabbit anti-Drosophila erecta (Fruit fly) Amyrel Polyclonal Antibody
Sign In for Pricing
View Details 
P1001-97EX-PE 100 µL
P130Cas (Cas for Crk-associated substrate, BCAR1, K-associated Substrate, Breast Cancer anti-estrogen Resistance 1 Protein) (BSA & Azide Free) (PE) discontinued
Sign In for Pricing
View Details MBS734289-01 48 Well
Canine Phospholipase A1 Activating Protein ELISA Kit
Sign In for Pricing
View Details 
MBS734289-02 96 Well
Canine Phospholipase A1 Activating Protein ELISA Kit
Sign In for Pricing
View Details